Neurologic

Traumatic spinal cord injury (SCI) continues to be a devastating injury to affected individuals and their families and exacts an enormous financial, psychological and emotional cost to them and to society. Despite years of research, the cure for paralysis remains elusive and current treatment is limited to early administration of high dose steroids and acute surgical intervention to minimize cord edema and the subsequent cascade of secondary delayed injury.

Traumatic brain injury (TBI) is a critical public health and socio-economic problem throughout the world.

Many cases of head injury, mainly associated to mild TBI, are not recognized by health professionals or are not reported by the patients themselves, so it is called “silent epidemic” because the data reported by epidemiological studies are largely incomplete

There are many kinds of impairments that may occur as a result of TBI. These injuries may impair:

• cognition — concentration, memory, judgment, and mood
• movement abilities — strength, coordination, and balance
• sensation — tactile sensation and special senses such as vision
• TBI sometimes results in seizure disorders (epilepsy). About 1 percent of persons with severe TBI survive in a state of persisting unconsciousness. There is no way to describe fully the human costs of traumatic brain injury: the burdens borne by those who are injured and their families.

Multiple sclerosis (MS) is an inflammatory disease of the central nervous system (CNS) of autoimmune pathogenesis, characterized by demyelination, oligodendrocyte apoptosis and axonal loss, resulting in significant disability. The care of subjects with MS has been revolutionized over the past 30 years, from no treatment available until 1993, when interferon-beta 1b was approved in the US, to 13 disease-modifying drugs approved in 2018. Patients in the relapsing and remitting phase of the disease may respond to a number of effective immunotherapies, although significant risks of immunomodulation including progressive multifocal leukoencephalopathy or secondary  autoimmune  diseases have been reported [1].

Cerebral palsy (CP) is one of the leading causes of childhood disability and affects the individual’s development and ability to function CP encompasses a group of movement disorders and affects posture. Motor limitations are attributed to a static disturbance in the developing brain, often accompanied by associated impairments and secondary health conditions. Despite new developments in the field of obstetrics and perinatology, incidence of CP is reported as out of 1,000 live births in premature deliveries and 1.1 out of 1,000 live births in mature babies (40 weeks’ gestation)

Intervertebral disc degeneration, or degenerative disc disease, is a major cause of lower back pain that typically occurs with age. In this process, the intervertebral discs (IVDs) undergo changes that affect their ability to act as shock absorbers. Due to undetermined reasons, the discs slowly lose their normal protein and water content and become replaced with fibrocartilage. As a result, the disc morphology changes and ultimately leads to a decrease in disc height, making the spine less stable and causing more pressure on the posterior elements of the spine.

Results of the therapy always depend on a condition and individual profile. Expected improvements:

• Increased energy
• Improved memory
• Better balance and coordination
• Improved gait and mobility
• Increased sexual function
• Reduced medications