Autistic spectrum disorders

Individuals with autism spectrum disorder (ASD) suffer from developmental disabilities that impact communication, behavior, and social interaction. Although the clinical presentation of this disorder varies in the presence and intensity of the signs and symptoms displayed, children with ASD typically present repetitive behavior and speech patterns, as well as de ficites in social interactions and verbal/nonverbal communication. Additionally, anxiety, attention-deficit/hyperactivity disorder, motor impairments (e.g., hypotonia, clumsiness, toe-walking), sleep disorders (e.g., insomnia), intellectual disability, and gastrointestinal problems (e.g., chronic constipation, diarrhea, abdominal pain) are also associated with ASD.

Immune dysregulation has been linked to children with ASD, manifesting in the form of altered T-cell responses, elevated plasma cytokine levels, and significantly lower plasma levels of transforming growth factor β -1, among others. In particular, intestinal immune dysregulation and gastrointestinal symptoms have been observed in children with ASD.


Why mesenchymal stem cells treatment?

Mesenchymal stem cells (MSCs) have immune-modulatory and anti-inflammatory properties and have been safely used in the treatment of a variety of neurological and autoimmune conditions. In particular, MSCs derived from the Wharton’s jelly of umbilical cord tissue (UC-MSCs) may possess greater immune-modulatory activity and proliferative capacity compared with other MSCs [3]. Some studies to date have demonstrated the safety of treatment that included MSCs [4]: of note, the results of a study by Sharma et al. showed that the majority (96%) of children with ASD treated with bone marrow-derived cells including MSCs.

 

Allogeneic stem cells can be administered multiple times over the course of days in uniform dosages, they are immune system privileged, cell rejection is not an issue and Human Leukocyte Antigen (HLA) matching is not necessary.

No need to collect stem cells from the patient’s hip bone or fat under anesthesia, which especially for small children and their parents, can be an unpleasant ordeal.

No need to administer chemotherapy drugs like granulocyte-colony stimulating factor (G-CSF or GCSF) to stimulate the bone marrow to produce granulocytes and stem cells and release them into the bloodstream.

These are promising and positive results indeed and our patients will have an available solution for combating ageing-related conditions and improved quality of life.

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Impact of therapy

The Stem Cell treatment of such conditions in QR Health Solutions is provided within NeuroQR program.

Results of the therapy always depend on a condition and individual profile. Expected improvements:

  • Better balance and coordination
  • Reduced medications
  • Increasing the quality of life.

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consultation

Just fill the application and one of our specialists will contact you by e-mail, phone, or any other convenient way for you. We will be happy to answer all your questions and provide the necessary information.

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