Stem Cells

Stem Cells: Application in Modern Medicine

Stem cells are used in regenerative medicine to support tissue repair, reduce inflammation, and regulate immune processes. They are part of comprehensive treatment programmes across various medical fields.

Main areas of application:

neurology and cardiology
orthopaedics and joint disorders
autoimmune and inflammatory conditions
rehabilitation after injuries and surgical procedures

The effectiveness and safety of cellular therapy are based on the individual selection of cell type, dosage, and proper medical supervision.

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What Are Stem Cells?

Stem cells are specialised cells of the body capable of self-renewal and differentiation. That is, transformation into various specialised tissue cells.
Throughout life, they participate in natural renewal processes: replacing damaged cells, supporting tissue regeneration, and maintaining the proper functioning of the body.
With age, both the number and activity of stem cells gradually decrease. This is one of the reasons why regenerative processes slow down and the body becomes less resilient to disease and stress factors.

We Select the Most Appropriate Stem Cells for You

In our cellular therapy programmes, we use advanced cell-based products derived from umbilical cord blood or mesenchymal stem cells (MSCs) that support the body in safely activating natural regenerative processes and reducing inflammation.

All cellular products are prepared in our own biotechnology laboratory and delivered to the clinic through our in-house logistics service, ensuring full quality control at every stage.

The number of cells and the administration protocol are determined by the physician based on clinical indications.

Types of stem cells

Mesenchymal Stem Cells (MSCs) from the Umbilical Cord and Placenta

Umbilical Cord Blood Stem Cells (UCBSCs)
Ethical Collection of Biological Material

Autologous Stem Cells from Adipose Tissue, Bone Marrow, Hair Follicles, and Peripheral Blood

Ethical collection of donor umbilical cord and placenta tissue is performed after the birth of a healthy child.
The procedure is safe and does not affect the condition of either the mother or the newborn.

Umbilical cord blood is collected immediately after childbirth and following the separation of the newborn from the umbilical cord and placenta, without any intervention in the body of the mother or the child.

The collection of these stem cells is performed directly from the adult patient and is therefore not associated with ethical concerns.

The procurement of autologous stem cells requires a medical procedure and may be accompanied by temporary discomfort and a short recovery period.

Before use, donor cells undergo multi-level laboratory quality control, including:

testing for infectious diseases
assessment of cell viability
sterility control
exclusion of genetic abnormalities within the cells

This ensures a high level of safety in cellular therapy for the patient.

Both the donor’s venous blood and the collected cord blood undergo comprehensive laboratory testing, including:

infectious disease screening
molecular testing and phenotyping
assessment of cell quality and viability
sterility control

This ensures the safety of the cellular product for the patient.

Advantages of Autologous MSCs:

full compatibility with the patient’s body
infectious safety
generally lower cost compared to donor-derived cells

Autologous mesenchymal stromal cells (most commonly derived from adipose tissue) are used in programmes of regenerative medicine, orthopaedics, rehabilitation, and aesthetic medicine.

Perinatal MSCs are biologically the youngest among adult stem cells and:

possess high therapeutic potential
have not been exposed to environmental factors
are infection-safe

For this reason, they are considered more effective in regenerative medicine compared to many other adult donor cell types.

Umbilical cord blood contains several types of stem cells, predominantly haematopoietic (blood-forming) stem cells, as well as biologically active factors and fetal haemoglobin.

It is used:

for transplantation as an alternative to bone marrow
in regenerative medicine
for immune system restoration and regulation

Cord blood cells may be combined with mesenchymal stromal cells (MSCs) to enhance the therapeutic effect.

The quality of autologous MSCs may decrease under the influence of the following factors:

patient age
autoimmune and chronic inflammatory diseases
metabolic disorders (obesity, diabetes, etc.)
harmful habits (smoking, alcohol consumption, etc.)

MSCs derived from the umbilical cord and placenta are well tolerated by the patient’s body.

This means:

a minimal risk of immune rejection
safe application across various clinical programmes

It is precisely this immune tolerance that has made MSCs the foundation of most modern cellular therapies.

For regenerative medicine programmes, cord blood cells are selected taking into account blood group and Rh factor compatibility between the donor and the patient.

The optimal option is the use of autologous or related donor material stored in a private biobank, which ensures maximum compatibility and safety.

Autologous MSCs are an excellent option for many individuals, but not always the optimal one.

For this reason, we often recommend:

using autologous cells in younger and generally healthy patients
selecting donor-derived MSCs in age-related or chronic conditions
combining approaches to achieve better outcomes

To date, thousands of clinical studies worldwide have been conducted using perinatal mesenchymal stromal cells.

They are being studied in the fields of:

regenerative medicine
immunomodulatory therapy
recovery after tissue damage
treatment of inflammatory and autoimmune conditions

This makes MSCs one of the most extensively studied cell types in modern biomedicine.

Umbilical cord blood stem cells have officially approved clinical protocols in several medical fields and are also used in modern cellular therapy programmes in accordance with international quality and safety standards.

Autologous mesenchymal stromal cells are активно studied worldwide and are used in programmes of regenerative medicine, orthopaedics, and rehabilitation. However, universal international protocols for all areas of application do not currently exist, and therefore cellular therapy is selected individually according to the patient’s clinical situation.

Why Mesenchymal Stromal Cells?

Optimal Balance of Effectiveness and Safety

MSCs have a favourable immunological profile, are well tolerated by the body, and are widely used in modern regenerative medicine.

Multidirectional Therapeutic Potential

Mesenchymal stromal cells influence several key mechanisms of recovery simultaneously: they reduce inflammation, regulate immune responses, and stimulate tissue regeneration.This multidirectional activity is what makes them a valuable tool in modern regenerative medicine.

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Optimal Balance of Effectiveness and Safety

MSCs have a favourable immunological profile, are well tolerated by the body, and are widely used in modern regenerative medicine.

Multidirectional Therapeutic Potential

Self-Renewal (Proliferation)

Mesenchymal stem cells possess the ability for self-renewal they can divide repeatedly without losing their functional properties.

They can also differentiate, meaning they are capable of transforming into various specialized cell types (bone, cartilage, adipose, muscle, and nerve cells), thereby supporting the body’s natural tissue repair processes.

Immunosuppressive / immunomodulatory

Mesenchymal stromal cells are capable of regulating immune system activity and helping the body maintain immune balance.
As a result, they reduce chronic inflammation, which often underlies pain, tissue damage, and the progression of many diseases.

Improvement of Tissue Quality and “Rejuvenating” Effect

MSCs promote tissue renewal and reduce inflammatory processes, which clinically manifests as improved structure and function.

For this reason, MSCs are used in regenerative and aesthetic medicine programs as a restorative tool.

Stimulation of Blood Circulation and Vascular Regeneration (Angiogenic Effect)

They promote the formation of new blood vessels and improve blood supply to damaged tissues.

This means organs and tissues receive more oxygen and nutrients, accelerating healing, reducing pain, and improving functional recovery after injuries, inflammation, or chronic circulatory disorders.

Paracrine Effect (Secretion of Bioactive Factors)

MSCs release growth factors and signaling molecules that initiate repair processes in the patient’s tissues.

This mechanism contributes to maintaining a long-term therapeutic effect after cell administration.

Neuroprotective Effect

They support nerve cells and promote the restoration of nervous tissue.

This is particularly important in neurological disorders, age-related changes, injuries, and trauma.

Regenerative Capacity

They are able to identify areas of damage within the body and differentiate into appropriate cell types.

They activate the body’s natural processes of cellular, tissue, and organ repair.

Where Do We Source Stem Cells?

We manufacture cellular products in our own biotechnology complex, Hemafund, ensuring full laboratory quality and safety control at every stage from donor material selection to the final cell-based product.
All cells undergo multi-level testing, including infectious, immunological, and genetic screening.

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Patient Benefits

Access to Unique Cell Sources

The possibility to use umbilical cord blood stem cells and mesenchymal stromal cells derived from the umbilical cord and placenta — among the most promising sources in regenerative medicine.

Over 20 Years of Practical Experience

More than two decades of expertise in cell technologies, biobanking, and manufacturing of cellular products.

Quality Control at Every Stage

Comprehensive laboratory, immunological, and genetic testing of all cellular materials.

Option of Autologous Cell Therapy

Use of the patient’s own stem cells, when medically indicated, as part of a personalized therapeutic strategy.

Individualized Cell Therapy Programs

The type of cells, dosage, and treatment protocol are determined by the physician based on clinical indications, patient preferences, and therapeutic goals.